2467 PRMT5 is a master epigenetic regulator to promote repair of radiation-induced DNA damage

OBJECTIVES/SPECIFIC AIMS: We recently reported that PRMT5 epigenetically activates androgen receptor (AR) in prostate cancer cells. Because targeting AR signaling through androgen deprivation therapy is clinically used as a radiosensitization approach to treat high-risk prostate cancer, our finding...

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Detalles Bibliográficos
Autor principal: Owens, Jake L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2018
Materias:
Basic/Translational Science/Team Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798993/
http://dx.doi.org/10.1017/cts.2018.109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798993/
http://dx.doi.org/10.1017/cts.2018.109

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