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2091: Evaluating the validity and utility of surrogate endpoints in clinical trials of chronic kidney disease (CKD)

OBJECTIVES/SPECIFIC AIMS: The objective of this research is to determine under what conditions endpoints based on estimated glomerular filtration rate (eGFR) slope or on relatively small declines in eGFR provide valid and useful surrogate endpoints for pivotal clinical trials in chronic kidney disea...

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Detalles Bibliográficos
Autores principales: Ying, Jian, Redd, Andrew, Greene, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799112/
http://dx.doi.org/10.1017/cts.2017.92