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3071 Cell Survival in Corneal Endothelial Dystrophies

OBJECTIVES/SPECIFIC AIMS: Purpose - The goal of this study is to understand how loss of the membrane protein SLC4A11 alters endothelial cell metabolism thereby producing Corneal Endothelial Dystrophy. Studies from our lab indicated that glutamine-dependent mitochondrial dysfunction is one of the out...

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Detalles Bibliográficos
Autores principales: Shyam, Rajalekshmy, Ogando, Diego, Choi, Moonjung, Bonanno, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799184/
http://dx.doi.org/10.1017/cts.2019.12