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2464 Sexual dimorphism in a mouse model of syndromic thoracic aortic aneurysm

OBJECTIVES/SPECIFIC AIMS: Pre-clinical and clinical observations have noted that increased aortic dilation is associated with male sex. Using an experimental model of severe, syndromic thoracic aortic aneurysms, we quantify aortic dilation and elastin stability in male Versus female mice. METHODS/ST...

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Detalles Bibliográficos
Autores principales: Chen, Zheying, Daugherty, Alan, Sheppard, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799199/
http://dx.doi.org/10.1017/cts.2018.121