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3173 A Mouse Model to Study Image-Guided, Radiation-Induced Cardiac Injury and Potential Clinically Targetable Biologic Mediators

OBJECTIVES/SPECIFIC AIMS: The overall objective of this study is to develop a novel, clinically-relevant, image-guided mouse model for radiation-induced cardiotoxicity, which can be used to gain insight into clinically-targetable, pathophysiologic mechanisms of cardiac injury in thoracic radiotherap...

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Detalles Bibliográficos
Autores principales: Dreyfuss, Alexandra, Verginadis, Ioannis, Shoniyozov, Khayrullo, Bravo, Paco, Feigenberg, Steven, Ky, Bonnie, Koumenis, Constantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799244/
http://dx.doi.org/10.1017/cts.2019.230