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2532: Predictive metabolism studies of varenicline and implications of its metabolites in nicotine addiction

OBJECTIVES/SPECIFIC AIMS: The central goal is to predict the metabolites of varenicline and predictively evaluate their propensities for eliciting an increased binding effect in the brain. METHODS/STUDY POPULATION: Molecular modeling computational software and other cheminformatic tools present a st...

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Detalles Bibliográficos
Autores principales: Thompson, Keeshaloy, Brown, Milton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799732/
http://dx.doi.org/10.1017/cts.2017.291