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2337: Doxorubicin exposure in vitro stimulates ROS production and directly suppresses cardiac fibroblast proliferation

OBJECTIVES/SPECIFIC AIMS: Our research strives to understand the pathophysiology of doxorubicin cardiotoxicity, focusing on the understudied nonmyocyte cardiac cells. Our understanding will enable researchers to develop protective or alternative therapies for cancer patients and treatments for cance...

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Detalles Bibliográficos
Autores principales: Mancilla, Trevi A., Aune, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799773/
http://dx.doi.org/10.1017/cts.2017.41