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Potent delivery of an MMP inhibitor to the tumor microenvironment with thermosensitive liposomes for the suppression of metastasis and angiogenesis

Metastasis is a major cause of chemotherapeutic failure and death. Degradation of a specific component of the extracellular matrix (ECM) by matrix metalloproteinases (MMPs) affects the physical barrier of the tumor microenvironment (TME) and induces metastasis. Here, lysolipid-containing thermosensi...

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Detalles Bibliográficos
Autores principales: Lyu, Yaqi, Xiao, Qingqing, Yin, Lifang, Yang, Lei, He, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799847/
https://www.ncbi.nlm.nih.gov/pubmed/31637006
http://dx.doi.org/10.1038/s41392-019-0054-9