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Dynamic enhancers control skeletal muscle identity and reprogramming

Skeletal muscles consist of fibers of differing metabolic activities and contractility, which become remodeled in response to chronic exercise, but the epigenomic basis for muscle identity and adaptation remains poorly understood. Here, we used chromatin immunoprecipitation sequencing of dimethylate...

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Detalles Bibliográficos
Autores principales: Ramachandran, Krithika, Senagolage, Madhavi D., Sommars, Meredith A., Futtner, Christopher R., Omura, Yasuhiro, Allred, Amanda L., Barish, Grant D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799888/
https://www.ncbi.nlm.nih.gov/pubmed/31589602
http://dx.doi.org/10.1371/journal.pbio.3000467