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An alternative approach for estimating the number needed to treat for survival endpoints

To investigate the issues of the NNT based on the absolute risk reduction (ARR), namely NNT(ARR); and to propose an alternative definition and an estimation procedure based on the restricted mean survival time (RMST), namely NNT(RMST), for RCTs. Three recent clinical trials with survival endpoints,...

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Detalles Bibliográficos
Autores principales: Yang, Zhao, Yin, Guosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799908/
https://www.ncbi.nlm.nih.gov/pubmed/31626655
http://dx.doi.org/10.1371/journal.pone.0223301