Avian oncogenic herpesvirus antagonizes the cGAS-STING DNA-sensing pathway to mediate immune evasion

The cellular DNA sensor cGMP-AMP synthase (cGAS) detects cytosolic viral DNA via the stimulator of interferon genes (STING) to initiate innate antiviral response. Herpesviruses are known to target key immune signaling pathways to persist in an immune-competent host. Marek’s disease virus (MDV), a hi...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Kai, Liu, Yongzhen, Xu, Zengkun, Zhang, Yu, Luo, Dan, Gao, Yulong, Qian, Yingjuan, Bao, Chenyi, Liu, Changjun, Zhang, Yanping, Qi, Xiaole, Cui, Hongyu, Wang, Yongqiang, Gao, Li, Wang, Xiaomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799934/
https://www.ncbi.nlm.nih.gov/pubmed/31539404
http://dx.doi.org/10.1371/journal.ppat.1007999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799934/
https://www.ncbi.nlm.nih.gov/pubmed/31539404
http://dx.doi.org/10.1371/journal.ppat.1007999

Ejemplares similares