A 3D Human Tri-Culture System Modeling Neurodegeneration and Neuroinflammation in Alzheimer’s Disease

Alzheimer’s disease (AD) is characterized by beta-amyloid (Aβ) accumulation, phosphorylated tau (p-tau) formation, hyper-activation of glial cells, and neuronal loss. The mechanisms of AD pathogenesis, however, remain poorly understood partially due to the lack of relevant human models that can comp...

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Detalles Bibliográficos
Autores principales: Park, Joseph, Wetzel, Isaac, Marriott, Ian, Dréau, Didier, D’Avanzo, Carla, Kim, Doo Yeon, Tanzi, Rudolph E., Cho, Hansang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800152/
https://www.ncbi.nlm.nih.gov/pubmed/29950669
http://dx.doi.org/10.1038/s41593-018-0175-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800152/
https://www.ncbi.nlm.nih.gov/pubmed/29950669
http://dx.doi.org/10.1038/s41593-018-0175-4

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