T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells

A recent neoadjuvant vaccine trial for early breast cancer induced strong Th1 immunity against the HER-2 oncodriver, complete pathologic responses in 18% of subjects, and for many individuals, dramatically reduced HER-2 expression on residual disease. To explain these observations, we investigated a...

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Detalles Bibliográficos
Autores principales: Namjoshi, Prachi, Showalter, Lori, Czerniecki, Brian J., Koski, Gary K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800266/
https://www.ncbi.nlm.nih.gov/pubmed/31666931
http://dx.doi.org/10.18632/oncotarget.10298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800266/
https://www.ncbi.nlm.nih.gov/pubmed/31666931
http://dx.doi.org/10.18632/oncotarget.10298

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