Muscle acetylcholine receptor conversion into chloride conductance at positive potentials by a single mutation

Charge selectivity forms the basis of cellular excitation or inhibition by Cys-loop ligand-gated ion channels (LGICs), and is essential for physiological receptor function. There are no reports of naturally occurring mutations in LGICs associated with the conversion of charge selectivity. Here, we r...

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Detalles Bibliográficos
Autores principales: Cetin, Hakan, Epstein, Max, Liu, Wei W., Maxwell, Susan, Rodriguez Cruz, Pedro M., Cossins, Judith, Vincent, Angela, Webster, Richard, Biggin, Philip C., Beeson, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800317/
https://www.ncbi.nlm.nih.gov/pubmed/31570625
http://dx.doi.org/10.1073/pnas.1908284116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800317/
https://www.ncbi.nlm.nih.gov/pubmed/31570625
http://dx.doi.org/10.1073/pnas.1908284116

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