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A triple drug combination targeting components of the nutrient-sensing network maximizes longevity

Increasing life expectancy is causing the prevalence of age-related diseases to rise, and there is an urgent need for new strategies to improve health at older ages. Reduced activity of insulin/insulin-like growth factor signaling (IIS) and mechanistic target of rapamycin (mTOR) nutrient-sensing sig...

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Detalles Bibliográficos
Autores principales: Castillo-Quan, Jorge Iván, Tain, Luke S., Kinghorn, Kerri J., Li, Li, Grönke, Sebastian, Hinze, Yvonne, Blackwell, T. Keith, Bjedov, Ivana, Partridge, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800352/
https://www.ncbi.nlm.nih.gov/pubmed/31570569
http://dx.doi.org/10.1073/pnas.1913212116