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Srrm234, but not canonical SR and hnRNP proteins, drive inclusion of Dscam exon 9 variable exons

Alternative splicing of pre-mRNA is a major mechanism to diversify protein functionality in metazoans from a limited number of genes. The Drosophila melanogaster Down syndrome cell adhesion molecule (Dscam) gene, which is important for neuronal wiring and phagocytosis of bacteria, can generate up to...

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Detalles Bibliográficos
Autores principales: Ustaoglu, Pinar, Haussmann, Irmgard U., Liao, Hongzhi, Torres-Mendez, Antonio, Arnold, Roland, Irimia, Manuel, Soller, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800468/
https://www.ncbi.nlm.nih.gov/pubmed/31292260
http://dx.doi.org/10.1261/rna.071316.119