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Distinct substrate specificities of the human tRNA methyltransferases TRMT10A and TRMT10B
The tRNA m(1)R(9) methyltransferase (Trm10) family is conserved throughout Eukarya and Archaea. Despite the presence of a single Trm10 gene in Archaea and most single-celled eukaryotes, metazoans encode up to three homologs of Trm10. Several disease states correlate with a deficiency in the human ho...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800469/ https://www.ncbi.nlm.nih.gov/pubmed/31292261 http://dx.doi.org/10.1261/rna.072090.119 |