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tailfindr: alignment-free poly(A) length measurement for Oxford Nanopore RNA and DNA sequencing

Polyadenylation at the 3′-end is a major regulator of messenger RNA and its length is known to affect nuclear export, stability, and translation, among others. Only recently have strategies emerged that allow for genome-wide poly(A) length assessment. These methods identify genes connected to poly(A...

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Detalles Bibliográficos
Autores principales: Krause, Maximilian, Niazi, Adnan M., Labun, Kornel, Torres Cleuren, Yamila N., Müller, Florian S., Valen, Eivind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800471/
https://www.ncbi.nlm.nih.gov/pubmed/31266821
http://dx.doi.org/10.1261/rna.071332.119