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Sequestration of microRNA-mediated target repression by the Ago2-associated RNA-binding protein FAM120A

Argonaute (Ago) proteins interact with various binding partners and play a pivotal role in microRNA (miRNA)-mediated silencing pathways. By utilizing immunoprecipitation followed by mass spectrometry to determine cytoplasmic Ago2 protein complexes in mouse embryonic stem cells (mESCs), we identified...

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Detalles Bibliográficos
Autores principales: Kelly, Timothy J., Suzuki, Hiroshi I., Zamudio, Jesse R., Suzuki, Megumu, Sharp, Phillip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800481/
https://www.ncbi.nlm.nih.gov/pubmed/31289130
http://dx.doi.org/10.1261/rna.071621.119