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Sequestration of microRNA-mediated target repression by the Ago2-associated RNA-binding protein FAM120A
Argonaute (Ago) proteins interact with various binding partners and play a pivotal role in microRNA (miRNA)-mediated silencing pathways. By utilizing immunoprecipitation followed by mass spectrometry to determine cytoplasmic Ago2 protein complexes in mouse embryonic stem cells (mESCs), we identified...
Autores principales: | Kelly, Timothy J., Suzuki, Hiroshi I., Zamudio, Jesse R., Suzuki, Megumu, Sharp, Phillip A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800481/ https://www.ncbi.nlm.nih.gov/pubmed/31289130 http://dx.doi.org/10.1261/rna.071621.119 |
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