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Adapting the engine to the fuel: mutator populations can reduce the mutational load by reorganizing their genome structure
BACKGROUND: Mutators are common in bacterial populations, both in natural isolates and in the lab. The fate of these lineages, which mutation rate is increased up to 100 ×, has long been studied using population genetics models, showing that they can spread in a population following an environmental...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800497/ https://www.ncbi.nlm.nih.gov/pubmed/31627727 http://dx.doi.org/10.1186/s12862-019-1507-z |