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Adapting the engine to the fuel: mutator populations can reduce the mutational load by reorganizing their genome structure

BACKGROUND: Mutators are common in bacterial populations, both in natural isolates and in the lab. The fate of these lineages, which mutation rate is increased up to 100 ×, has long been studied using population genetics models, showing that they can spread in a population following an environmental...

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Detalles Bibliográficos
Autores principales: Rutten, Jacob Pieter, Hogeweg, Paulien, Beslon, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800497/
https://www.ncbi.nlm.nih.gov/pubmed/31627727
http://dx.doi.org/10.1186/s12862-019-1507-z