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Editosome RNase III domain interactions are essential for editing and differ between life cycle stages in Trypanosoma brucei
Multiprotein editosomes catalyze gRNA-specified insertion and deletion of uridines to create functional mitochondrial mRNAs in Trypanosoma brucei. Three functionally distinct editosomes are distinguished by their single KREN1, KREN2, or KREN3 RNase III endonuclease and, respectively, KREPB8, KREPB7,...
Autores principales: | McDermott, Suzanne M., Carnes, Jason, Stuart, Kenneth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800513/ https://www.ncbi.nlm.nih.gov/pubmed/31171708 http://dx.doi.org/10.1261/rna.071258.119 |
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