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Impact of SLCO1B3 Polymorphisms on Clinical Outcomes in Lung Allograft Recipients Receiving Mycophenolic Acid

Single nucleotide polymorphisms (SNPs) in genes involved in mycophenolic acid (MPA) metabolism have been shown to contribute to variable MPA exposure, but their clinical effects are unclear. We aimed to determine if SNPs in key genes in MPA metabolism affect outcomes after lung transplantation. We p...

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Detalles Bibliográficos
Autores principales: Tague, Laneshia K., Byers, Derek E, Hachem, Ramsey, Kreisel, Daniel, Krupnick, Alexander S., Kulkarni, Hrishikesh S., Chen, Catherine, Huang, Howard J, Gelman, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800829/
https://www.ncbi.nlm.nih.gov/pubmed/30992538
http://dx.doi.org/10.1038/s41397-019-0086-0