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A mathematical solution to Peto’s paradox using Polya’s urn model: implications for the aetiology of cancer in general
Ageing is the leading risk factor for the emergence of cancer in humans. Accumulation of pro-carcinogenic events throughout life is believed to explain this observation; however, the lack of direct correlation between the number of cells in an organism and cancer incidence, known as Peto’s Paradox,...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800849/ https://www.ncbi.nlm.nih.gov/pubmed/30771154 http://dx.doi.org/10.1007/s12064-019-00290-6 |