Cargando…

Pharmacokinetic/pharmacodynamic assessment of a novel, pharmaceutical lipid–aspirin complex: results of a randomized, crossover, bioequivalence study

Aspirin (acetylsalicylic acid, ASA) can lead to gastrointestinal mucosal injury through disruption of its protective phospholipid bilayer. A liquid formulation of a novel pharmaceutical lipid–aspirin complex (PL-ASA) was designed to prevent this disruption. We sought to determine the pharmacokinetic...

Descripción completa

Detalles Bibliográficos
Autores principales: Angiolillo, Dominick J., Bhatt, Deepak L., Lanza, Frank, Cryer, Byron, Dong, Jin-fei, Jeske, Walter, Zimmerman, Ronald R., von Chong, Estela, Prats, Jayne, Deliargyris, Efthymios N., Marathi, Upendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800884/
https://www.ncbi.nlm.nih.gov/pubmed/31420787
http://dx.doi.org/10.1007/s11239-019-01933-7