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Serum neurofilament heavy chains as early marker of motor neuron degeneration

OBJECTIVE: To determine whether serum phosphorylated neurofilament heavy chain (pNfH) levels are elevated before patients were diagnosed with sporadic or familial ALS, and what the prognostic value of these prediagnostic pNfH levels is. METHODS: pNfH was measured via ELISA in leftovers of serum draw...

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Detalles Bibliográficos
Autores principales: De Schaepdryver, Maxim, Goossens, Janne, De Meyer, Steffi, Jeromin, Andreas, Masrori, Pegah, Brix, Britta, Claeys, Kristl G., Schaeverbeke, Jolien, Adamczuk, Katarzyna, Vandenberghe, Rik, Van Damme, Philip, Poesen, Koen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801162/
https://www.ncbi.nlm.nih.gov/pubmed/31518073
http://dx.doi.org/10.1002/acn3.50890