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Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis

BACKGROUND: Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD(+))-dependent protein deacetylase that is involved in various diseases, including cancers, metabolic diseases, and inflammation-associated diseases. However, the role of SIRT1 in ulcerative colitis (UC) is still confusing. AIM...

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Detalles Bibliográficos
Autores principales: Ren, Meng-Ting, Gu, Meng-Li, Zhou, Xin-Xin, Yu, Mo-Sang, Pan, Hang-Hai, Ji, Feng, Ding, Chen-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801188/
https://www.ncbi.nlm.nih.gov/pubmed/31636473
http://dx.doi.org/10.3748/wjg.v25.i38.5800