Crystal structures of CDC21-1 inteins from hyperthermophilic archaea reveal the selection mechanism for the highly conserved homing endonuclease insertion site

Self-splicing inteins are mobile genetic elements invading host genes via nested homing endonuclease (HEN) domains. All HEN domains residing within inteins are inserted at a highly conserved insertion site. A purifying selection mechanism directing the location of the HEN insertion site has not yet...

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Detalles Bibliográficos
Autores principales: Beyer, Hannes M., Mikula, Kornelia M., Kudling, Tatiana V., Iwaï, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2019
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801210/
https://www.ncbi.nlm.nih.gov/pubmed/31363851
http://dx.doi.org/10.1007/s00792-019-01117-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801210/
https://www.ncbi.nlm.nih.gov/pubmed/31363851
http://dx.doi.org/10.1007/s00792-019-01117-4

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