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NeurodegenERation: The Central Role for ER Contacts in Neuronal Function and Axonopathy, Lessons From Hereditary Spastic Paraplegias and Related Diseases

The hereditary spastic paraplegias (HSPs) are a group of inherited neurodegenerative conditions whose characteristic feature is degeneration of the longest axons within the corticospinal tract which leads to progressive spasticity and weakness of the lower limbs. Though highly genetically heterogene...

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Detalles Bibliográficos
Autores principales: Fowler, Philippa C., Garcia-Pardo, M. Elena, Simpson, Jeremy C., O’Sullivan, Niamh C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801308/
https://www.ncbi.nlm.nih.gov/pubmed/31680803
http://dx.doi.org/10.3389/fnins.2019.01051