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Sperm IZUMO1-Dependent Gamete Fusion Influences Male Fertility in Mice

Sperm–egg fusion is accomplished through the interaction of a specific set of membrane proteins in each gamete: sperm IZUMO1 and oocyte JUNO. Recently, we found that alternative splicing of the Izumo1 gene generates a novel IZUMO1 isoform (IZUMO1_v2). Here, we obtained four mouse lines, having grade...

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Detalles Bibliográficos
Autores principales: Saito, Takako, Wada, Ikuo, Inoue, Naokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801368/
https://www.ncbi.nlm.nih.gov/pubmed/31569716
http://dx.doi.org/10.3390/ijms20194809