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APP, PSEN1, and PSEN2 Mutations in Asian Patients with Early-Onset Alzheimer Disease

The number of patients with Alzheimer’s disease (AD) is rapidly increasing in Asia. Mutations in the amyloid protein precursor (APP), presenilin-1 (PSEN1), and presenilin-2 (PSEN2) genes can cause autosomal dominant forms of early-onset AD (EOAD). Although these genes have been extensively studied,...

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Detalles Bibliográficos
Autores principales: Giau, Vo Van, Bagyinszky, Eva, Youn, Young Chul, An, Seong Soo A., Kim, SangYun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801447/
https://www.ncbi.nlm.nih.gov/pubmed/31557888
http://dx.doi.org/10.3390/ijms20194757