Novel Hsp90 Inhibitor C086 Potently Inhibits Non-Small Cell Lung Cancer Cells As A Single Agent Or In Combination With Gefitinib

PURPOSE: Inhibition of heat shock protein 90 (Hsp90) can lead to degradation of multiple client proteins, which are involved in tumor progression. Elevated Hsp90 expression has been linked to poor prognosis in patients with non-small cell lung cancer (NSCLC). Discovery of effective drug is a promisi...

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Detalles Bibliográficos
Autores principales: Wang, Liman, Fan, Yingjuan, Mei, Hanhao, Liu, Yang, Zhang, Lianru, Xu, Jianhua, Huang, Xuhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801566/
https://www.ncbi.nlm.nih.gov/pubmed/31802936
http://dx.doi.org/10.2147/CMAR.S215970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801566/
https://www.ncbi.nlm.nih.gov/pubmed/31802936
http://dx.doi.org/10.2147/CMAR.S215970

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