Investigation of Phospholipase Cγ1 Interaction with SLP76 Using Molecular Modeling Methods for Identifying Novel Inhibitors

The enzyme phospholipase C gamma 1 (PLCγ1) has been identified as a potential drug target of interest for various pathological conditions such as immune disorders, systemic lupus erythematosus, and cancers. Targeting its SH3 domain has been recognized as an efficient pharmacological approach for dru...

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Detalles Bibliográficos
Autores principales: Tripathi, Neha, Vetrivel, Iyanar, Téletchéa, Stéphane, Jean, Mickaël, Legembre, Patrick, Laurent, Adèle D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801593/
https://www.ncbi.nlm.nih.gov/pubmed/31548507
http://dx.doi.org/10.3390/ijms20194721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801593/
https://www.ncbi.nlm.nih.gov/pubmed/31548507
http://dx.doi.org/10.3390/ijms20194721

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