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STAT3 Regulates the Type I IFN-Mediated Antiviral Response by Interfering with the Nuclear Entry of STAT1

Signal transducer and activator of transcription 3 (STAT3) is a multifunctional factor that regulates inflammation and immunity. Knowledge of its regulatory mechanisms is very limited. Here, we showed that enterovirus 71 (EV71) infection induced the phosphorylation of STAT3 and the expression of its...

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Detalles Bibliográficos
Autores principales: Wang, Huanru, Yuan, Meng, Wang, Shuaibo, Zhang, Li, Zhang, Rui, Zou, Xue, Wang, Xiaohui, Chen, Deyan, Wu, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801597/
https://www.ncbi.nlm.nih.gov/pubmed/31575039
http://dx.doi.org/10.3390/ijms20194870