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Processing and Maturation of Cathepsin C Zymogen: A Biochemical and Molecular Modeling Analysis

Cysteine cathepsin C (CatC) is a ubiquitously expressed, lysosomal aminopeptidase involved in the activation of zymogens of immune-cell-associated serine proteinases (elastase, cathepsin G, proteinase 3, neutrophil serine proteinase 4, lymphocyte granzymes, and mast cell chymases). CatC is first syn...

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Detalles Bibliográficos
Autores principales: Lamort, Anne-Sophie, Hamon, Yveline, Czaplewski, Cezary, Gieldon, Artur, Seren, Seda, Coquet, Laurent, Lecaille, Fabien, Lesner, Adam, Lalmanach, Gilles, Gauthier, Francis, Jenne, Dieter, Korkmaz, Brice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801622/
https://www.ncbi.nlm.nih.gov/pubmed/31557781
http://dx.doi.org/10.3390/ijms20194747