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Prognostic Factors and Biomarkers of Responses to Immune Checkpoint Inhibitors in Lung Cancer

Manipulation of the immune response is a game changer in lung cancer treatment, revolutionizing management. PD1 and CTLA4 are dynamically expressed on different T cell subsets that can either disrupt or sustain tumor growth. Monoclonal antibodies (MoAbs) against PD1/PDL1 and CTLA4 have shown that in...

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Detalles Bibliográficos
Autores principales: Bianco, Andrea, Perrotta, Fabio, Barra, Giusi, Malapelle, Umberto, Rocco, Danilo, De Palma, Raffaele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801651/
https://www.ncbi.nlm.nih.gov/pubmed/31590386
http://dx.doi.org/10.3390/ijms20194931