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Human Cysteine Cathepsins Degrade Immunoglobulin G In Vitro in a Predictable Manner

Cysteine cathepsins are critical components of the adaptive immune system involved in the generation of epitopes for presentation on human leukocyte antigen (HLA) molecules and have been implicated in degradation of autoantigens. Immunoglobulin variable regions with somatic mutations and random comp...

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Detalles Bibliográficos
Autores principales: Høglund, Rune Alexander, Torsetnes, Silje Bøen, Lossius, Andreas, Bogen, Bjarne, Homan, E. Jane, Bremel, Robert, Holmøy, Trygve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801702/
https://www.ncbi.nlm.nih.gov/pubmed/31569504
http://dx.doi.org/10.3390/ijms20194843