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Human Cysteine Cathepsins Degrade Immunoglobulin G In Vitro in a Predictable Manner
Cysteine cathepsins are critical components of the adaptive immune system involved in the generation of epitopes for presentation on human leukocyte antigen (HLA) molecules and have been implicated in degradation of autoantigens. Immunoglobulin variable regions with somatic mutations and random comp...
Autores principales: | Høglund, Rune Alexander, Torsetnes, Silje Bøen, Lossius, Andreas, Bogen, Bjarne, Homan, E. Jane, Bremel, Robert, Holmøy, Trygve |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801702/ https://www.ncbi.nlm.nih.gov/pubmed/31569504 http://dx.doi.org/10.3390/ijms20194843 |
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