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iPSC-Derived Embryoid Bodies as Models of c-Met-Mutated Hereditary Papillary Renal Cell Carcinoma

Hereditary cancers with cancer-predisposing mutations represent unique models of human oncogenesis, as a driving oncogenic event is present in germline. Currently, there are no satisfactory models to study these malignancies. We report the generation of IPSC from the somatic cells of a patient with...

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Detalles Bibliográficos
Autores principales: Hwang, Jin Wook, Desterke, Christophe, Féraud, Olivier, Richard, Stephane, Ferlicot, Sophie, Verkarre, Virginie, Patard, Jean Jacques, Loisel-Duwattez, Julien, Foudi, Adlen, Griscelli, Frank, Bennaceur-Griscelli, Annelise, Turhan, Ali G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801716/
https://www.ncbi.nlm.nih.gov/pubmed/31575031
http://dx.doi.org/10.3390/ijms20194867