Identification of New DR5 Agonistic Nanobodies and Generation of Multivalent Nanobody Constructs for Cancer Treatment

Current cancer therapeutics suffer from a lack of specificity in targeting tumor cells and cause severe side effects. Therefore, the design of highly specialized drugs comprising antibody derivatives inducing apoptosis in targeted cancer cells is considered to be a promising strategy. Drugs acting o...

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Detalles Bibliográficos
Autores principales: Sadeghnezhad, Golnaz, Romão, Ema, Bernedo-Navarro, Robert, Massa, Sam, Khajeh, Khosro, Muyldermans, Serge, Hassania, Sadegh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801735/
https://www.ncbi.nlm.nih.gov/pubmed/31569768
http://dx.doi.org/10.3390/ijms20194818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801735/
https://www.ncbi.nlm.nih.gov/pubmed/31569768
http://dx.doi.org/10.3390/ijms20194818

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