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Identification of New DR5 Agonistic Nanobodies and Generation of Multivalent Nanobody Constructs for Cancer Treatment
Current cancer therapeutics suffer from a lack of specificity in targeting tumor cells and cause severe side effects. Therefore, the design of highly specialized drugs comprising antibody derivatives inducing apoptosis in targeted cancer cells is considered to be a promising strategy. Drugs acting o...
Autores principales: | Sadeghnezhad, Golnaz, Romão, Ema, Bernedo-Navarro, Robert, Massa, Sam, Khajeh, Khosro, Muyldermans, Serge, Hassania, Sadegh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801735/ https://www.ncbi.nlm.nih.gov/pubmed/31569768 http://dx.doi.org/10.3390/ijms20194818 |
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