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A Generalized Kinetic Model for Coupling between Stepping and ATP Hydrolysis of Kinesin Molecular Motors

A general kinetic model is presented for the chemomechanical coupling of dimeric kinesin molecular motors with and without extension of their neck linkers (NLs). A peculiar feature of the model is that the rate constants of ATPase activity of a kinesin head are independent of the strain on its NL, i...

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Detalles Bibliográficos
Autores principales: Xie, Ping, Guo, Si-Kao, Chen, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801755/
https://www.ncbi.nlm.nih.gov/pubmed/31623357
http://dx.doi.org/10.3390/ijms20194911