Exogenous Iron Increases Fasciocidal Activity and Hepatocellular Toxicity of the Synthetic Endoperoxides OZ78 and MT04

The synthetic peroxides OZ78 and MT04 recently emerged as fasciocidal drug candidates. However, the effect of iron on fasciocidal activity and hepatocellular toxicity of these compounds is unknown. We investigated the in vitro fasciocidal activity and hepatocellular toxicity of OZ78 and MT04 in abse...

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Detalles Bibliográficos
Autores principales: Brecht, Karin, Kirchhofer, Carla, Bouitbir, Jamal, Trapani, Francesca, Keiser, Jennifer, Krähenbühl, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801819/
https://www.ncbi.nlm.nih.gov/pubmed/31581457
http://dx.doi.org/10.3390/ijms20194880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801819/
https://www.ncbi.nlm.nih.gov/pubmed/31581457
http://dx.doi.org/10.3390/ijms20194880

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