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Conditional Knockdown of Osteopontin Inhibits Breast Cancer Skeletal Metastasis

High osteopontin (OPN) expression is linked to breast cancer bone metastasis. In this study we modulated osteopontin levels conditionally and investigated any related antineoplastic effects. Therefore, we established cell clones from human breast cancer MDA-MB-231 cells, in which the expression of O...

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Detalles Bibliográficos
Autores principales: Kovacheva, Marineta, Zepp, Michael, Schraad, Muriel, Berger, Stefan, Berger, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801824/
https://www.ncbi.nlm.nih.gov/pubmed/31590218
http://dx.doi.org/10.3390/ijms20194918