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A Novel HDL-Mimetic Peptide HM-10/10 Protects RPE and Photoreceptors in Murine Models of Retinal Degeneration

Age-related macular degeneration (AMD) is a leading cause of blindness in the developed world. The retinal pigment epithelium (RPE) is a critical site of pathology in AMD. Oxidative stress plays a key role in the development of AMD. We generated a chimeric high-density lipoprotein (HDL), mimetic pep...

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Detalles Bibliográficos
Autores principales: Su, Feng, Spee, Christine, Araujo, Eduardo, Barron, Eric, Wang, Mo, Ghione, Caleb, Hinton, David R., Nusinowitz, Steven, Kannan, Ram, Reddy, Srinivasa T., Farias-Eisner, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801888/
https://www.ncbi.nlm.nih.gov/pubmed/31569695
http://dx.doi.org/10.3390/ijms20194807