Replication Stress at Telomeric and Mitochondrial DNA: Common Origins and Consequences on Ageing

Senescence is defined as a stress-induced durable cell cycle arrest. We herein revisit the origin of two of these stresses, namely mitochondrial metabolic compromise, associated with reactive oxygen species (ROS) production, and replicative senescence, activated by extreme telomere shortening. We di...

Descripción completa

Detalles Bibliográficos
Autores principales: Billard, Pauline, Poncet, Delphine A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801922/
https://www.ncbi.nlm.nih.gov/pubmed/31597307
http://dx.doi.org/10.3390/ijms20194959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801922/
https://www.ncbi.nlm.nih.gov/pubmed/31597307
http://dx.doi.org/10.3390/ijms20194959

Ejemplares similares