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Dec1 Deficiency Suppresses Cardiac Perivascular Fibrosis Induced by Transverse Aortic Constriction

Cardiac fibrosis is a major cause of cardiac dysfunction in hypertrophic hearts. Differentiated embryonic chondrocyte gene 1 (Dec1), a basic helix–loop–helix transcription factor, has circadian expression in the heart; however, its role in cardiac diseases remains unknown. Therefore, using Dec1 knoc...

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Detalles Bibliográficos
Autores principales: Le, Hue Thi, Sato, Fuyuki, Kohsaka, Akira, Bhawal, Ujjal K., Nakao, Tomomi, Muragaki, Yasuteru, Nakata, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802004/
https://www.ncbi.nlm.nih.gov/pubmed/31597354
http://dx.doi.org/10.3390/ijms20194967