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The repurposing of type I-E CRISPR-Cascade for gene activation in plants

CRISPR-Cas systems are robust and facile tools for manipulating the genome, epigenome and transcriptome of eukaryotic organisms. Most groups use class 2 effectors, such as Cas9 and Cas12a, however, other CRISPR-Cas systems may provide unique opportunities for genome engineering. Indeed, the multi-su...

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Detalles Bibliográficos
Autores principales: Young, Joshua K., Gasior, Stephen L., Jones, Spencer, Wang, Lijuan, Navarro, Pedro, Vickroy, Becca, Barrangou, Rodolphe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802105/
https://www.ncbi.nlm.nih.gov/pubmed/31646186
http://dx.doi.org/10.1038/s42003-019-0637-6