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Resident memory T cells are a cellular reservoir for HIV in the cervical mucosa

HIV viral reservoirs are established very early during infection. Resident memory T cells (T(RM)) are present in tissues such as the lower female genital tract, but the contribution of this subset of cells to the pathogenesis and persistence of HIV remains unclear. Here, we show that cervical CD4(+)...

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Detalles Bibliográficos
Autores principales: Cantero-Pérez, Jon, Grau-Expósito, Judith, Serra-Peinado, Carla, Rosero, Daniela A., Luque-Ballesteros, Laura, Astorga-Gamaza, Antonio, Castellví, Josep, Sanhueza, Tamara, Tapia, Gustavo, Lloveras, Belen, Fernández, Marco A., Prado, Julia G., Solé-Sedeno, Josep M., Tarrats, Antoni, Lecumberri, Carla, Mañalich-Barrachina, Laura, Centeno-Mediavilla, Cristina, Falcó, Vicenç, Buzon, Maria J., Genescà, Meritxell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802119/
https://www.ncbi.nlm.nih.gov/pubmed/31628331
http://dx.doi.org/10.1038/s41467-019-12732-2