Cargando…
Resident memory T cells are a cellular reservoir for HIV in the cervical mucosa
HIV viral reservoirs are established very early during infection. Resident memory T cells (T(RM)) are present in tissues such as the lower female genital tract, but the contribution of this subset of cells to the pathogenesis and persistence of HIV remains unclear. Here, we show that cervical CD4(+)...
Autores principales: | Cantero-Pérez, Jon, Grau-Expósito, Judith, Serra-Peinado, Carla, Rosero, Daniela A., Luque-Ballesteros, Laura, Astorga-Gamaza, Antonio, Castellví, Josep, Sanhueza, Tamara, Tapia, Gustavo, Lloveras, Belen, Fernández, Marco A., Prado, Julia G., Solé-Sedeno, Josep M., Tarrats, Antoni, Lecumberri, Carla, Mañalich-Barrachina, Laura, Centeno-Mediavilla, Cristina, Falcó, Vicenç, Buzon, Maria J., Genescà, Meritxell |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802119/ https://www.ncbi.nlm.nih.gov/pubmed/31628331 http://dx.doi.org/10.1038/s41467-019-12732-2 |
Ejemplares similares
-
Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab
por: Serra-Peinado, Carla, et al.
Publicado: (2019) -
Identification of HIV-reservoir cells with reduced susceptibility to antibody-dependent immune response
por: Astorga-Gamaza, Antonio, et al.
Publicado: (2022) -
KLRG1 expression on natural killer cells is associated with HIV persistence, and its targeting promotes the reduction of the viral reservoir
por: Astorga-Gamaza, Antonio, et al.
Publicado: (2023) -
Dendritic Cells From the Cervical Mucosa Capture and Transfer HIV-1 via Siglec-1
por: Perez-Zsolt, Daniel, et al.
Publicado: (2019) -
A Novel Single-Cell FISH-Flow Assay Identifies Effector Memory CD4(+) T cells as a Major Niche for HIV-1 Transcription in HIV-Infected Patients
por: Grau-Expósito, Judith, et al.
Publicado: (2017)